Pancreatic Cancer Survival Time

Pancreatic cancer is usually a diagnosis which means the survival of the patient is in months or a couple of years. The tumours which originate from the pancreas are locally advanced by the time it is even detected by the usual clinical methods. The tumour may also spread to distant organs in advanced cases. The symptoms of pancreatic cancer are very few and they are seen only when the cancer is locally advanced. This makes the pancreatic cancer survival time much less as compared to other cancers. According to the American Cancer Society, for all stages of pancreatic cancer combined, the one-year relative survival rate is 20%, and the five-year rate is 5%. Even for those with local disease the 5-year relative survival rate is only 16%.

Overall, fewer than 5% of all patients are still alive 5 years after initial diagnosis. The collective median survival time of all patients is 4-6 months. The best predictors of long-term survival after surgery are a tumour diameter of less than 3 cm, no nodal involvement, and negative resection margins. The staging of pancreatic cancer is the best indicator of survival of a patient. The pancreatic cancer survival time depends on the extent to which the cancer has invaded the body. Local or resectable cancer which comprises about ten percent of all cases has the best cancer survival time. In this case the disease is confined only to the pancreas and is clearly separated from the surrounding blood vessels. The treatment options are surgery, and chemotherapy and radiation post operative. The median survival time in this stage is 17 months.

When the patient is in the second stage the cancer is usually so locally advanced that it cannot be removed by surgery. This means the cancer encases or compresses blood vessels which make surgery impossible. The cancer may also invade and destroy the surrounding organs. This stage makes up about 30% of all pancreatic cancer cases. The treatment in this case is usually chemotherapy which is most commonly gemcitabine-based and may be combined with radiation. This type of multi – modality therapy is associated with better survival rates. In very rare instances, cancers that respond well to initial treatment may subsequently be surgically resected. The pancreatic cancer survival time in this case is eight or nine months.

The last stage has the worst pancreatic cancer survival time. This is called the metastatic stage where the cancer is not limited to the surrounding organs but also affects distant ones. The liver is most commonly involved in this stage and the chances of survival in this stage are very bleak. Unfortunately, most cases of pancreatic cancer are diagnosed in this stage only. Approximately 60% of all pancreatic cancer cases are in the metastatic stage where chemotherapy is the only modality available. Gemcitabine based chemotherapy is the standard treatment in this stage where the median survival time is 4 to 6 months. The therapy also aims at relieving patient symptoms like jaundice or bowel obstruction with surgery and medication to relieve pain.

This Summer, Make Skin Cancer Awareness and Prevention a Priority

National Skin Cancer Awareness Month is observed nationwide each May in an effort to educate the public about the dangers of skin cancer. Despite widespread warnings of the risks associated with unprotected sun exposure, approximately two million people will be diagnosed with skin cancer this year. About 68,000 of these cases will be melanoma, the most serious type of skin cancer.

“The annual rates of all forms of skin cancer are increasing each year, representing a growing public health concern,” says Ashley Record, MD. “It has been estimated that nearly half of all Americans who live to age 65 will develop skin cancer at least once in their lives.”

There are three main types of skin cancer: non-melanoma basal cell carcinoma, non-melanoma squamous cell carcinoma, and melanoma.
Non-melanoma basal cell carcinoma and non-melanoma squamous cell carcinoma are usually found on sun-exposed areas of the body, such as the face, ears, neck, lips and back of the hands. They typically don’t spread to other parts of the body and have a high likelihood of being cured if detected and treated early.
Melanoma is much more serious and is the most common type of skin cancer among young adults. Originating in the melanocytes – the cells that produce skin coloring and pigmentation – melanoma is often below the surface and, therefore, more difficult to detect and diagnose. Malignant melanoma accounts for about 8,700 of the 11,790 skin cancer-related deaths each year.

According to the American Cancer Society, skin cancer is often curable, if caught and treated in its early stages. Its symptoms include:
– Any change in the size or color of a mole or other darkly pigmented growth or spot;
– Any new skin growth;
– Scaliness, oozing, bleeding or change in the overall appearance of a bump or nodule;
– The spread of pigmentation beyond a growth’s border, such as dark coloring that spreads past the edge of a mole or mark; or
– A change in sensation, itchiness, tenderness or pain of a growth or spot.

Although unprotected sun exposure has been strongly linked to skin cancer, the American Cancer Society suggests these other skin cancer risk factors:
– Unprotected and/or excessive exposure to ultraviolet (UV) radiation, such as that used in a tanning bed;
– Occupational exposures to coal tar, pitch, creosote, arsenic compounds or radium;
– Fair complexion;
– Family history;
– Multiple or atypical moles; and
– A history of severe sunburns.

“An awareness of risk factors, coupled with regular skin exams, can greatly reduce your chances of developing skin cancer,” says Dr. Record. “And if you have a suspicious-looking mark or mole, talk to your doctor sooner rather than later. It’s better to be overly cautious than to ignore a potential problem.”

Dr. Record suggests these tips for helping prevent skin cancer:
– Avoid prolonged sun exposure, especially between 10 a.m. and 4 p.m.
– Use a sunscreen with an SPF of 15+ every day.
– When going outside for extended periods, reapply sunscreen every two hours and cover up, including a broad-rimmed hat and UV-blocking clothing and sunglasses, whenever possible.
– Keep newborns out of the sun and remember that sunscreens should only be used on babies over the age of six months.
– Examine your skin from head-to-toe every month, and see your physician for a professional skin exam every year.

For more information or to schedule an appointment with Dr. Record, call Advanced Dermatology at 654-1124.

Knowing the Signs of Genital Warts

Condylomata acuminata is a medical condition caused by the human papillomavirus or HPV. It is sexually transmitted and occurs in 50% of sexually active adults across the US. It is more popularly known as genital warts or venereal warts.

1. What is HPV?

HPV is a serious infection. There over a hundred known strains of HPV, some are low-risk that can cause warts, others are high-risk and are known to cause the dreaded cervical cancer as well as anal and other genital cancers.

HPV is transmitted through contact with the skin or mucosal membrane of an infected person during sexual activity. A latency stage may occur for months or even years from onset of the infection in which no symptom is evident.

2. Symptoms

Genital warts are lumps that vary in appearance. Most warts are flesh or gray in color, often round, sometimes cauliflower in shape, and may be varied in size. Sometimes the bumps are hardly noticeable as they can grow smaller than the tip of a ballpoint pen.

In women, the growths may appear on the vulva, in the walls of vagina or inside the cervix. In men, they commonly occur on the tip and sometimes the shaft of the penis, or on the scrotum. The growth can likewise occur inside and on the periphery of the anus, in the area of the groin, and the inner thighs in both men and women. Rarely, the warts can grow in the mouth or inside the throat as caused by oral sex with a carrier of the disease.

The warts may cause itching and irritation in the areas where they occur. They may likewise cause bleeding during sexual intercourse. Warts may weaken the walls of the vagina and compromise its stretchability which is crucial to childbirth.

In exceptional cases, an infected mother may transmit the virus to her child during natural vaginal birth. In such cases, the infected child may develop growth in the airway, a condition called respiratory papillomatosis. This is a dangerous situation that may call for a surgical incision to remove the airway blockage.

3. Common Misdiagnosis

It is important to know the signs of genital warts as there are a few diseases with similar symptoms that are commonly mistaken for venereal warts. There are somewhat similar lesions called hirsuties papillaris genitalis in men and vestibular papillae of the vulva in women that are actually benign though abnormal skin conditions.

Another common skin condition called Fordyce spots can be observed on the penis or vulva and may likewise be mistaken for warts. Likewise, there is a viral infection known as molluscum contagiosum that is sexually transmitted in adults and shows similar pearly lesions in the genital area. This disease, on the other hand, is less harmful than venereal warts.

4. Treatment

Genital warts can occasionally cause irritation, itching and bleeding, but more importantly, they are seen as consistent source of embarrassment so many people opt to have them removed. There are prescription topical medications such as Imiquimod, Podophyllin and 5-fluorouracil that can remove the lesions.

There are also doctor-performed procedures such as cauterization, cryosurgery, surgical incision and laser removal. Taking out genital warts, however, does not guarantee elimination of the viral infection. Thus, the warts may clear altogether after treatment or recur or even worsen over time.

Manhattan Dental Implants Experts Talk About the Effects of Smoking on Oral Health, PART 2

Welcome to the second installment of this two-part article series on the impacts of smoking upon one’s oral health. In Part 1, we spoke to a Manhattan dental implants surgeon who highlighted the following deleterious health impacts:Smoking or chewing tobacco stains and discolors your teeth.Smoking irritates the soft tissue in the mouth, causing it to become red and inflamed.Smoking impedes the healthy production of saliva in the mouth; a condition known as “dry mouth”.Smoking causes halitosis or chronic bad breath.

In spite of this impressive list, we’re yet to get to the very worst of the health implications of being a smoker, so let’s jump right in…Smoking affects the immune system and slows the rate of healing

“Smoking compromises the body’s ability to fight infection. It also restricts the normal flow of blood to the gums, which not only slows healing; it also reduces the supply of vital minerals and nutrients to the gums and teeth,” says the Manhattan dental implants surgeon. “Delayed healing is a considerable problem for patients getting dental work done, such as dental implants, since the risk of post-operative infection and implant failure is much greater for smokers than for non-smokers.”Smoking causes gum disease

“Through the irritation of the oral soft tissues, the reduction of saliva production and the impediment of blood flow to the gums, smoking often leads to the development of gum disease,” says the “All On 4®” implants expert. “Gum disease is characterized by a pervasive bacterial infection of the gums and the supporting structures of the teeth. Over time and left without treatment, it destroys the bone and ligaments that supports the tooth roots, causing them to become loose. Eventually, your teeth will fall out altogether.”

Smokers are six times more likely to develop gum disease than non-smokers, according to results attained by a dental research team at the University of Newcastle upon Tyne, UK.Smoking causes oral cancer, amongst a host of other cancers

The connection between smoking and oral cancer is well documented in the medical literature. Chronic inflammation leads to a greater risk of cancer. If you are a smoker, it is heavily advised that you see your dentist twice a year and make a special mention of your habit. “Ask your dentist to perform oral cancer screenings as a precaution,” advises the Manhattan dental implants surgeon. “Early detection is the key to the best possible chances of complete recovery. If you have noticed any oral sores that don’t heal, or abnormal lumps or lesions, seek immediately professional attention.”

What Can I Do?

No matter which way you look at it, smoking and staying healthy are mutually exclusive. Don’t be swayed by those people’s stories about their great grandfather who smoked 40 a day and died at the age of 95. While such cases may exist, they are the exception rather than the rule. “To protect your oral (and general) health, you should quit smoking,” says the all on 4 implants expert. “If you don’t, anything a dental healthcare practitioner tries to do to fix any problems will most likely be in vain.”

“Additionally, whether you currently smoke or have just given up, you will need to go over and above the norm to keep your teeth and gums clean and free from bacteria. Brush and floss thoroughly every day and consider augmenting your home oral hygiene routine with an anti-septic mouthwash. If you want to avoid an appointment with the Manhattan dental implants surgeon, book regular appointments with your regular dentist and oral hygienist. Prevention is always better and cheaper than cure.”

Fatih Uckun Professor of Research at the Keck School of Medicine

A Professor of Research at the Keck School of Medicine of the University of Southern California in its Department of Pediatrics and an Adjunct Professor of Pediatrics in the Selçuklu School of Medicine, Selçuk University in Konya, Turkey, Dr. Fatih Uckun has previously served for 13 years as a researcher and professor at the University of Minnesota. His medical interests lie in developmental therapeutics and biopharmaceuticals, especially in the area of pediatric cancers and leukemia.

Dr. Fatih Uckun has co-authored more than 470 papers in peer-reviewed journals such as Science, Nature, New England Journal of Medicine, and the Proceedings of the National Academy of Sciences. The U.S. Patent Office and its European counterpart have recognized more than 83 inventions devised by Dr. Fatih Uckun. These include tyrosine kinase inhibitors, natural compounds, and organic metallic compounds against cancer. Much in demand as a lecturer, Dr. Fatih Uckun will give presentations in 2011 on such topics as nanomedicine and cancer nanotechnology at Providence Saint Joseph Medical Center in Burbank and the Gordon Research Conference in Waterville, Maine.

Dr. Fatih Uckun holds memberships in the American Association for Cancer Research (AACR), the American Society of Hematology (ASH), and the Radiation Research Society (RRS). In 1996, the American Society for Clinical Investigation (ASCI), a prestigious honor society of physician-scientists, recognized Dr. Fatih Uckun’s achievements by admitting him to membership. Since then, he has become a member of the American Society of Clinical Oncology (ASCO). Dr. Fatih Uckun has worked with government agencies, including his current affiliation with the NCI Alliance for Nanotechnology in Cancer, and in the past, the U.S. Department of Defense and DARPA (Defense Advanced Research Projects Agency), serving as a Principal Investigator on a Virus Neutralizer Research Project grant

He is a senior physician-scientist who currently holds the academic post of Professor of Research in the Department of Pediatrics in the Keck School of Medicine of the University of Southern California. In addition, he serves as the Head of Translational Research in Leukemia and Lymphoma and the Leader of the Developmental Therapeutics Program within the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles.

Dr. Fatih Uckun also heads a federally funded Nanomedicine Research & Development Program at the Children’s Hospital Los Angeles. This program is affiliated with the National Cancer Institute Alliance on Nanotechnology against Cancer. Among his many ongoing duties, Dr. Fatih Uckun serves as a member of the Developmental Therapeutics Program Working Group of the USC Norris Comprehensive Cancer Center.

Dr. Fatih Uckun belongs to a number of medical associations, including the American Society for Clinical Investigation, an honor society for leading physician-scientists. He holds patents for more than 80 inventions, received numerous awards, including the Stohlman Memorial Award, the highest honor given by the Leukemia Society of America to its most productive scholars and has lectured at many prestigious organizations and conferences. He has published more than 400 articles in most prestigious peer-reviewed journals and written chapters for nearly 30 books, on many topics.

The Best Info Of Cancer Support

Support And Cancer.

You should join a support group when you have been diagnosed with cancer. You will be able to meet people who have been through what you are going through. You will be able to learn how they got through their situation and the things they did to cope. It can be very useful and helpful.

If you have cancer, join a support group. A support group can offer you valuable information, advice, and assistance. It also helps you to realize that you’re not alone in this battle. Support groups are available across the country, for every type of cancer. A simple Internet search should help you to locate one quickly.

While chemotherapy and radiation helps in your race for a cure, it also weakens your body. Therefore, it is essential that you have a support group to help you through this time in your life. Members should include someone who can help clean your home and help with the preparation of your meals, a handyman, and someone who you can open up and talk to.

A great way for cancer survivors to deal and to know what lies ahead is to network with other survivors. There are plenty of cancer survivors in the world, thankfully, and they meet up at support groups and even on internet forums, so you can always keep in contact with other survivors.

When coping with cancer, you need to seek support from your friends and family. Many people do not realize that their loved ones want to be there to support them through the rough journey and that they will do anything to help the cancer patient feel more relaxed, comfortable, and loved.

Seek out other people who have been diagnosed with cancer. They understand your situation and many of the feelings that you are having. While your friends and family members are wonderful, it may be difficult to talk to them about certain aspects of your treatment. There are a variety of local support groups and forums that you can find online.

If you have cancer, insurers will hesitate to insure you. Research your insurance options though. Your local government offices or cancer support organizations may have more options for you. Family and Medical Leave Act and Americans with Disabilities Act can be useful to you too.

Seeking support from a support group is important when you are battling cancer and getting help. You will be able to learn valuable information from people who have already been in your shoes. They will be able to tell you what they went through and what things really worked for them.

Talk with other survivors. A cancer diagnosis can be overwhelming and it can feel like no one understands what it is like. Talk with family members or friends who has gone through it themselves or join a support group. From them, you can get insight into what treatment will be like and how to handle your diagnosis.

If you are battling cancer, it can be helpful to join a support group for your type of cancer or cancer in general. Talking to others in your situation can help you feel less alone and give you a chance to make new friends. Mutual support can be very important on the journey to recovery.

Support Group.

If you have been recently diagnosed with cancer or have had it for some time I would highly suggest finding and joining a cancer support group. Cancer is one of the hardest diseases to deal with emotionally because it’s mortality rates. Having a support group will help you cope and enjoy your life the best you can.

Cancer is not only terrible for the person who is diagnosed with the disease, but it is awful for the family of that person as well. Find a support group for the entire family to go to, so that you will all be able to learn the best ways to cope with this disease and not break down while going through it.

Finding a support group that has others in it that are also dealing with cancer can be a very helpful thing. It will give you a safe place to talk about the fears that your family may not be ready to hear. You will also be able to help and support others going through a similar process.

Get a clear picture from your doctor about any limitations or changes you can expect to experience after undergoing cancer treatment. It is far easier to make plans to cope with these issue before receiving treatment. This is also the time to find a support group if you wish to join one.

When you are dealing with cancer, you want to have a sufficient support group. This support group can get you through the worst of times and even the best of times, offering the support that is needed and the motivation you need to continue with your treatment and therapy measures.

If you are not coping very well, or even if you are coping well, consider looking for a support group in your area. They will be able to listen and relate to what you are going through and you will likely find a good bit of comfort in being surrounded by others who are going or have been through the things that you are.

If you have recently found out that you have cancer, and you are not a religious person, you may want to consider getting into religion. Many people find comfort from religion and spirituality when they are going through cancer. Many churches and other places of worship have cancer support group.

Dealing with cancer can be a tough process to go through, but having a good support group around you will help to brighten your mood. Without support from loved ones, it can be a scary process dealing with cancer and one nobody should face alone. A support group will give you the motivation needed to fight this battle.

Of course, cancer prevention is only a small area of an incredibly large topic. But the more you know about cancer as a general topic, the better your odds become of successful dealing with it if you or someone you care about is diagnosed with this dangerous disease. Take the “Support” tips you’ve read above seriously.

Alimta: Associated Side Effects

Alimta is one of the key medications administered in combination with other drugs for the effective control of a malignant form of cancer. According to the facts put forth by the PMPRB or the Patented Medicine Prices Review Board, the introductory price of Alimta was found to be within the guidelines extended by them only because Canadian drug stores were successful in maintaining the prices at the same level as compared to other countries that were also selling the drug. Therefore, Canadian drug prices have a huge role to play in the overall price regulation of life saving medications such as these.

Alimta is also associated with several side effects, which patients need to be aware of, prior to consumption. The side effects can be classified into the common ones, which can be taken in one’s stride, and the serious ones, which warrant immediate medical attention. The normal side effects of Alimta might include common symptoms like feeling too tired or noticeable redness at the injection site. Others might include diarrhoea, nausea (which can sometimes result in vomiting), mouth ulcers, hair loss and even loss of appetite to a certain extent.

Alimta: Side Effects You Should Be Aware of

Besides the common side effects, Alimta is often associated with severe after effects with continual usage. Some such effects include:The first and probably most visually obvious effect could be severe allergic reactions. These can manifest in the form of skin eruptions, like rashes and hives. There could also be swelling of the face, tongue or lips, a feeling of tightness in the chest, breathing difficulties and the like. The patient should seek immediate medical attention on the occurrence of such symptoms.Other potentially serious side effects may occur in the form of high fever, sore throat, chills, persistent cough, etc. These flu-like symptoms might assume mammoth proportions if not attended to in time.If you have exceptional trouble in swallowing food, this could also be one of the side effects associated with this drug.Sometimes, you might notice unusual bleeding and peeling of the skin. This too could be due to the adverse impact of Alimta on your system. Seek immediate medical attention to combat such conditions.This cancer limiting drug can also leave significant impacts on your mental health. Some common side effects pertaining to the mental health include violent mood swings and mental changes, which cannot be logically explained. If such signs do appear, you need to start being a little cautious and continue to monitor the condition of the patient for distinct trends.Severe stomach pain could also be one of the more serious after effects of this drug. This could be extreme to the point of being unbearable.Urine retention or decrease in urine volume has also been associated with the continued use of this drug.Although these are the most common effects reported, this is by no means an exhaustive list of side effects that might occur due to consumption of Alimta. Case specific side effects might also occur.

Something on Prostate Cancer

If you have just learned that you have prostate cancer or know someone who has been diagnosed with it, you may be feeling depressed and angry. However such type of cancer can be treated and you can go on living a normal and healthy life again.

The treatment of prostate cancer can vary depending on the advancement of the disease, the patients physical state, and other factors. The first signs of Prostate cancer that someone can exhibit can be a difficulty in urinating, which occurs because the prostate gland swells up to such a large extent. This could be further divided into frequently getting up in the night to urinate, interrupted flow of urine, and no urine flow at all. There could also be blood in the urine, and a painful feeling in the hips, back and pelvis. Another symptom could present itself in painful ejaculation.

To give a prognosis for prostate cancer can also depend on if this is the first discovery of the caner or if it is a recurrence. Many different kinds of test are done to check for cancer cells. This includes a rectal examination, a probe or a less obtrusive ultra sound. Once you have been diagnosed, other tests will have to be performed to check if the cancer has spread to other areas of the body before a final diagnosis and treatment options can be given.

The severity and stage of the prostate cancer is referred to by the Gleason score, which is determined by the way the cancer tissue looks under a microscope. If the score is low it means that the tissue is normal and does not look like it will spread easily. If it is high however, then the likely hood that the cancer will spread to other areas of the body is likely.

Such type of cancer is usually found in older men and there are the usual treatments of surgery (where the lymph nodes are removed), Radiation therapy, and hormone therapy. There are also newer types of treatments for prostate cancer that are still in the clinical trial phase which include Chemotherapy, Cryosurgery, Biological therapy and a high intensity form of ultra sound.

If you have any of the above mentioned symptoms that could indicate related cancer then it would be wise to consult with your health care professional to ensure that if you do have prostate cancer it is discovered early and treated accordingly.

Cruciferous Vegetables, Cancer Beater – a Real Cancer Prevention Diet

If you smoke, or ever have, and you eat lots of broccoli (or other cruciferous veggies such as cabbage, cauliflower, kale, turnip greens, mustard greens or collard greens), you might be doing yourself a great favor in terms of lung cancer. This according to research just presented at the American Association of Cancer Research meeting held last week in Washington D.C. by a team from Roswell Park Cancer Institute of Buffalo, NY when they concluded cruciferous vegetables can helpful as part of a cancer prevention diet.

Li Tang, Ph.D., a post-doctoral fellow at Roswell Park Cancer Institute and colleagues conducted a hospital-based, case-controlled study of lung cancer cases matched with smoking status controls.

The study wasn’t focused on broccoli alone, but allowed for eating all the commonly consumed cruciferous vegetables – in either their raw or cooked forms. The study found that among smokers – and especially former smokers – higher intake of cruciferous vegetables was associated with a lower risk of lung cancer. Smokers who ate raw veggies saw the most benefit.

Researchers divided their findings into four subtypes of lung cancer. The strongest risk reduction was seen among subjects with squamous or small-cell carcinoma, the two types most strongly associated with heavy smoking.

“Broccoli is not a therapeutic drug, but for smokers who believe they cannot quit nor do anything about their risk, this is something positive,” Tang said. “People who quit smoking will definitely benefit more from intake of cruciferous vegetables.”

The percentage of Americans who smoke has fallen below 20% for the first time since the mid 1960s. If you smoke and you’re concerned about lung cancer risk, first and foremost, you need to stop. Get help quitting from support groups, nicotine replacement therapy, hypnosis or the variety of medications now available. If you have the will (or even if you’re not sure you do) getting cigarettes out of your life for good can save you not only money, but help you take solid, real-world steps to improve your health, today and over the long haul as well.

When you do quit, your lung capacity goes up and your bronchial tubes relax which makes breathing easier. Not only this, the poisonous carbon monoxide in your blood goes down so that your blood can carry more oxygen. Of course your sense of smell, the discoloration of your teeth, fingers and clothing will also improve noticeably. Best of all, the second hand smoke you’re sending into the environment will be eliminated – a healthy gift to everyone around you.

If you’re trying to quit, or can’t quite get there yet… eat as many of the cruciferous veggies as you enjoy from the list above, especially in their raw state as heating damages an important enzyme thought to activate the cancer fighting properties.

Earlier work released in February 2008 backed up these findings with results showing that compounds called isothiocyanates from these veggies could have cancer fighting properties. The research was on bladder cancer and supported animal studies that suggest broccoli and the other cruciferous vegetables have some cancer protecting abilities. Another study, out in July 2008, suggested a link between men who ate broccoli four times a week and a protective effect against prostate cancer.

So the real story here is that we should all try to increase our consumption of cruciferous vegetables whether we smoke or not as part of a cancer prevention diet.